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Intracytoplasmic Morphologically Selected Sperm Injection, more commonly referred to as IMSI is an assisted reproductive technique used to fertilise eggs in the IVF lab, when sperm defects are the cause of the infertility.

How is IMSI done?

In IMSI, the sperm sample is examined using an inverted microscope, to check for defects within the sperm head, as well as shape, size and motility abnormalities. This digitally enhanced microscope provides a much greater magnifying power (about 6000x magnification) compared to the one normally used in ICSI (200x). The embryologist selects healthy sperm from the sample, which is then injected into the inner part of the egg. Once it results in fertilisation, the embryo is implanted into the aspiring mother’s womb. However, since this is a selection process, it might not be suited to men with a very low sperm count.

“At Srushti Fertility Centre, we recommend IMSI for men with elevated levels of DNA fragmentation or who have a high percentage of abnormal sperm, couples who have had recurrent miscarriages, failed ICSI treatments or poorly developed embryos.

The treatment cycle is exactly the same as IVF and ICSI, but since the best sperm are selected, chances of conception are better.” – Dr.Divya Sivaraman, Fertility Consultant.